Tong, R., Mehendale, S. R., Wang, C. Z., Shao, Z., and Yuan, C. S. Comparison of antioxidant effects of various Scutellaria baicalensis fractions and the potential role of catalase upregulation. The herb is used for tumors. Wu, J. Zhou, X., Zhang, Q., Liang, H., Jiang, Y., Wang, X., Wang, B., and Zhao, Y. Takeshita K, Saisho Y, Kitamura K, et al. Kimura, Y., Okuda, H., and Ogita, Z. View abstract. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. It has the chemical formula C 21 H 11 O 18 and a molecular mass of 446,364 g/mol. View abstract. 2007;60(5-6):294-297. View abstract. Yoon, S. B., Lee, Y. J., Park, S. K., Kim, H. C., Bae, H., Kim, H. M., Ko, S. G., Choi, H. Y., Oh, M. S., and Park, W. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. 2004;50(3):279-285. Razina, T. G., Zueva, E. P., Litvinenko, V. I., and Kovalev, I. P. [A semisynthetic flavonoid from the Baikal skullcap (Scutellaria baicalensis) as an agent to enhance the efficacy of chemotherapy in experimental tumors]. Baikal skullcap might have an effect like a water pill or "diuretic." It thrives on sunny, grassy slopes in higher elevations. The dose of your diabetes medication might need to be changed. Clin Cancer Res 5-15-2005;11(10):3905-3914. Heals Allergic conditions. View abstract. J Biomed.Sci 2009;16:27. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. Here’s more about skullcap and the major benefits of this herb. 2004;91(1):65-68. Planta Med 2010;76(1):76-78. (Elite.Ed) 2010;2:1538-1547. 2011;10(2):184-191. View abstract. Zhongguo Zhong.Yao Za Zhi 2009;34(22):2910-2915. Zhong.Yao Cai. Baikal skullcap might lower blood pressure. View abstract. Taking Baikal skullcap might decrease how well the body gets rid of lithium. Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others. J AOAC Int 2009;92(3):785-788. Pharmacotherapy 2010;30(7):750, 258e-750, 262e. Other Common Names: Huang qin, baikal, baical skullcap root, scute, scutellaria. 6-29-2001;500(1-2):52-55. It has been extensively used as a medicinal plant in China for decades. View abstract. FEBS Lett. Planta Med 2000;66:91-3. Flavonoids in particular prevent the inflammatory processes in the body that lead to allergic reactions. View abstract. View abstract. Product name Aical skullcap root extract Latin Name scutellaria baicalensis Content saponins Specification 10:1 Appearance Brown Yellow Powder Mesh size 80 Mesh Used Part Whole herb Test Method UV & TLC International Journal of Pharmacology 2010;6(2):81-88. Zhang S, Cheng Z, Huang B, and Li J. View abstract. View abstract. Z., and Liu, Y. W. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. 2000;23(5):272-274. Nutr Res 2009;29:298-304. Baikal Skullcap is quite beneficial for insomnia and sleep disorders. View abstract. Skullcap herb has been used for generations in both Chinese and American medicine. A., Attele, A. S., Zhang, L., and Yuan, C. S. Anti-HIV activity of medicinal herbs: usage and potential development. Chan, E., Liu, X. X., Guo, D. J., Kwan, Y. W., Leung, G. P., Lee, S. M., and Chan, S. W. Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats. Zhang H, Huang J. A., Lee, K., Hwangbo, H., Park, E., Kim, M., and Ma, W. Detection of the potential adulterant Teucrium chamaedrys in Scutellaria baicalensis raw material and extract by high-performance thin-layer chromatography. [Study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. Chung, C. P., Park, J. Lin, X. C., Liu, X. G., Chen, X. W., Chen, W. Z., and Liang, N. C. [Inhibitory effect and its kinetic analysis of baicalein on recombinant human protein kinase CK2 holoenzyme]. Habitat: Chinese skullcap is native to eastern Asia. 2010;33(8):1265-1270. Gao, J., Morgan, W. A., Sanchez-Medina, A., and Corcoran, O. Skullcap is used for trouble sleeping (insomnia), anxiety, stroke, and paralysis caused by stroke. Scullcap is a plant also known as Baikal Scullcap, Chinese Skullcap, Escutelaria Asiatica, Huang Qin, Huangquin, Hwanggum, Ogon, Ou-gon, Racine de Scutellaire du Lac Baïkal, Radix Scutellariae, Scutellaire, Wogon, and other names. Nahrung 2004;48(2):123-128. Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Baikal Skullcap is a low growing herbaceous perennial shrub that normally grows about 30 cm in height, but spreading up to 50-60 cm wide. View abstract. View abstract. Tsao, T. F., Newman, M. G., Kwok, Y. Y., and Horikoshi, A. K. Effect of Chinese and western antimicrobial agents on selected oral bacteria. Stem is tetragonal, erect, branching near base, pubescent in the stem margins. Baikal Skullcap Health Benefits Antioxidant Antidisease Antibacterial Anti-inflammatory Antiviral Neuroprotective Astringent Fibrefuge Antipyretic Anticholesterolemic Haemostatic Sedative Tonic Int J Cancer 9-10-2003;106(4):559-565. View abstract. Biomed.Chromatogr. Kim, E. H., Shim, B., Kang, S., Jeong, G., Lee, J. S., Yu, Y. A., and Provalova, N. V. [The modulating effects of preparations of Baikal skullcap (Scutellaria baicalensis) on erythron reactions under conditions of neurotic exposures]. The health benefits of this herb will depend on the type of herb you are consuming. Chinese journal of modern developments in traditional medicine 1990;10(5):278-9. Zhongguo Ying.Yong.Sheng Li Xue.Za Zhi 2009;25(3):344-348. 1998;61(1):37-39. View abstract. The plant grows well in sandy, rocky soils and needs full sun, desert lands, waste and cultivated areas, Soil should be well drained, but should not dry out completely and does well in cultivated planting beds, 30cm in height, but spreading up to 50-60cm wide, 5–25 cm long, 0.5–3.0 cm in diameter, conical, twisted, or flattened root. View abstract. Potential Benefits of Using Skullcap Herb While not everyone will see relief from using Chinese or American skullcap, studies suggest some have seen positive results. Protective effect of baicalein extracted from Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice. Baikal skullcap (scientific name Scutellaria baicalensis) is a plant. Cheng, K. T., Hou, W. C., Huang, Y. C., and Wang, L. F. Baicalin induces differential expression of cytochrome C oxidase in human lung H441 cell. In Vivo 2004;18(4):497-503. Protective effect of scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by injection Aß25-35. Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells. Use 5 to 15 grams of the powdered root added to 1 cup of boiling water to make a tea. Skullcap gets its name from its blue to purplish-pink flowers that have a shape resembling a medieval knight’s helmet. It is useful to cure infections and inflammation of respiratory, digestive and urinary system. It is used to treat chronic inflammatory conditions such as asthma, arthritis and allergy. View abstract. View abstract. Food Chem Toxicol. Pharmacol.Res. Am J Chin Med 2006;34(2):245-261. View abstract. Vopr.Onkol. Skullcap has gained the most attention in recent times because of its calming potential that can help with pain, anxiety, and sleep. Zhou J, Qu F, Yu Y, et al. [Analysis of main flavonoids contents of Scutellaria baicalensis]. Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. View abstract. Other common names are huang-qin root, goldenroot, and Baikal skullcap. 2009;48(12):1159-1169. View abstract. Journal of Chinese medicinal materials 2002;25(6):451-453. View abstract. View abstract. The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis. View abstract. This nutrient’s roots have been used for thousands of years for other health benefits, and now we’re discovering that it also helps make your skin biologically younger. Jeong, K., Shin, Y. C., Park, S., Park, J. S., Kim, N., Um, J. Y., Go, H., Sun, S., Lee, S., Park, W., Choi, Y., Song, Y., Kim, G., Jeon, C., Park, J., Lee, K., Bang, O., and Ko, S. G. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. Phytochemistry 2011;72(8):752-760. Chinese skullcap also has shown aspirin-like anti-inflammatory qualities. 1990;36(5):602-607. 2009;29(1):211-213. Eksp.Klin Farmakol. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. J Ethnopharmacol. View abstract. The herb could prove useful as an herbal treatment for hepatitis. The plant can moderately withstand the harsh temperatures and grows easily. View abstract. Shim K.S, Kim S.N, Kim M.H, and et al. Gao Z, Huang K, Yang X, Xu H. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Baikal Skullcap Extract is mostly available in bulk powder form or as capsules. View abstract. BioPure Baikalin Powder is a powdered extract from the root of Scutellaria baicalensis, also known as Chinese Skullcap, Huang-Qin, or Baikal Skullcap. Pneumonitis induced by ou-gon (scullcap). Biol Pharm Bull 2004;27(10):1580-1583. Hu, J. Zhao, M., Zhou, Z. T., and Zhang, W. D. [Antifugal susceptibility testing and antifugal traditional Chinese medicines screening of oral Candida isolated from head and neck cancer patients treated with radiotherapy or chemotherapy]. Skullcap is the. View abstract. Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others. Its traditional use has been for microbial infections, inflammation, diarrhea, dysentery, hypertension, hemorrhaging, insomnia, cholesterol management, and respiratory infections. D.M. View abstract. View abstract. Park, K. I., Park, H. S., Kang, S. R., Nagappan, A., Lee, D. H., Kim, J. Mol Pharmacol 2001;60(3):507-513. Bleeding disorders. Cell Mol Biol Res 1993;39(2):119-124. Alcohol can cause sleepiness and drowsiness. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. [Effects of Honeysuckle flower and Scutellaria Baicalensis Georgi on constraction and electric activity of rabbit small intestine smooth muscle]. Gabrielska, J., Oszmianski, J., Zylka, R., and Komorowska, M. Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes. Cancer Sci 2011;102(4):870-876. Chinese skullcap (Scutellaria baicalensis) is an herb commonly used in traditional Chinese medicine. [Flavonoids from Scutellaria baicalensis and their bioactivities]. View abstract. Maternal and Child Health Care of China 2011;26(10):1529-1531. Not enough is known about the safety of Baikal skullcap in children when used long-term. View abstract. Baikal Skullcap is beneficial for dealing with allergic conditions like asthma, hay fever, eczema, and nettle rash. View abstract. View abstract. View abstract. View abstract. More research is required before recommending skullcap in humans. The plant blooms from July to August to produce blue-purple flowers that are helmet shaped on the upper part and have a skirt, wide like lobe on the underneath. Li T.T, Xu H.M, and Liang Z.W. Ceska.Slov.Farm. View abstract. View abstract. Vestn.Ross.Akad.Med Nauk 1995;(1):29-38. Cardiovasc.Res 2-1-2011;89(2):426-435. Morgan SL, Baggott JE, Morel, L, Desmond R, and Kendrach AC. It is also used for gastrointestinal (GI) infections, as well as liver problems including viral hepatitis and jaundice. 7-1-2005;382(1-2):71-75. Lin YK, Yen HR, Wong WR, et al. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. Some Skullcap constituents aid in promoting sleep , which makes it even more awesome – because while it’s providing protective benefits while you sleep, at the same time it’s also helping the body maintain healthy immune function. The dose of your metformin (Glucophage) might need to be changed. View abstract. View abstract. 2009;86(2):79-84. Lee, B. S., Shim, S. M., Heo, J., Pae, H. O., Seo, B. Y., Han, S. Y., Sohn, D. H., Jang, S. I., and Chung, H. T. Wogonin suppresses TARC expression induced by mite antigen via heme oxygenase 1 in human keratinocytes. View abstract. Bull Exp Biol Med 2002;134(1):47-49. Some of these medications that are changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin (Coumadin), and many others. Beijing Da.Xue.Xue.Bao. It prefers dry soils and does well in cultivated planting beds. J Agric Food Chem 1-12-2005;53(1):8-16. Morgan SL, Baggott JE, Moreland L, et al. In traditional Chinese Medicine this plant was used (almost always in combination with other plants or foods), to clear heat, dry damp, drain fire, and resolve toxins (it is used to support normal immune function). In traditional Chinese medicine, Baikal skullcap is “cold” and “bitter” herb. View abstract. It also enhanced the pancreatic insulin content as well as the lipid profile. View abstract. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. View abstract. Broncel, M. [Antiatherosclerotic properties of flavones from the roots of Scutellaria baicalensis Georgi]. View abstract. Diabetes medications are also used to lower blood sugar. Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. Although a number of laboratory and animal research showed that PC-SPES may prevent the growth of prostate cancer cells, it’s not known if those anticancer effects were due to the action of the herbs or the prescription medications. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Udintsev, S. N., Razina, T. G., and Iaremenko, K. V. [The antitumor effect of Baikal skullcap]. Immunopharmacology 2000;49:295-306. Lei, W., Sun, M., Luo, K. M., Shui, X. R., Sun, Y. M., and Tang, H. [Compute simulation to characterize structure and function of chalcone synthase from Scutellaria baicalensis Georgi]. Low blood pressure: Baikal skullcap might lower blood pressure. View abstract. Yin, F., Liu, J., Ji, X., Wang, Y., Zidichouski, J., and Zhang, J. Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Abeta aggregation in SH-SY5Y cells. View abstract. Martin, J. and Dusek, J. Buy Our Baicalin Supplement . Chen, H. H., Hong, H. J., Chou, Y. H., Cheng, T. H., Chen, J. J., and Lin, H. Inhibition of cyclic strain-induced endothelin-1 secretion by baicalein in human umbilical vein endothelial cells. Konoshima, T., Kokumai, M., Kozuka, M., Iinuma, M., Mizuno, M., Tanaka, T., Tokuda, H., Nishino, H., and Iwashima, A. View abstract. Int J Cancer 5-1-2007;120(9):2019-2027. Kimura, Y. and Sumiyoshi, M. Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. View abstract. A., Han, D. Y., and Kim, G. S. Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. Scutellaria baicalensis (Chinese Skullcap) is a traditional chinese medicine for the purposes of cardiovascular and cognitive health as well as longevity. Baikal Skullcap Extract has antibacterial, diuretic, anti-inflammatory, anti-metamorphosis and antispasmodic effects, and has a strong anti-cancer response to the physiological performance. Dosage varies by age, weight, health condition, and other medications taken. 1989;35(3):331-335. On the other hand, the Chinese skullcap, which is also called Baikal skullcap, is found majorly in south-east Asia and has the scientific name Scutellaria baicalensis. This antispasmodic activity makes it an extremely effective herb for menstrual cramps and it calming action aids PMT symptoms. It is used to clear heat and dry dampness. Wang, H. W., Lin, C. P., Chiu, J. H., Chow, K. C., Kuo, K. T., Lin, C. S., and Wang, L. S. Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin. Lee, C. Y., Wang, J. Y., Chen, T. C., Jiang, J. K., Peng, C. H., Kuo, C. D., Chang, W. C., Chiu, J. H., and Wu, C. W. Effects of S/B remedy containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on hepatic interleukin-6 related signal transducer and activator of transcription 3 activation in mice through cell-cell interaction. Drug Metab Dispos 2005;33:537-46. Baikal skullcap might cause sleepiness and drowsiness. Altern.Ther.Health Med. Int J Antimicrob.Agents 2009;34(3):284-285. 2006;5(1):9-29. Privacy Policy Leung, H. W., Yang, W. H., Lai, M. Y., Lin, C. J., and Lee, H. Z. Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. Learn about its benefits, usage, dosage recommendations as well as potential side effects. The pharmacology of Chinese herbs. Consult with your doctor before consuming it if you are suffering from diseases like blood diseases, abdominal pain, edema and menses scanty. It appears to be a good source for flavonoid compounds, and some Baikal skullcap might have some of the same effects as estrogen. Of small air passages in the body and boost your overall health, skullcap tea may be just the.. Offered by its potent antioxidant, anti-inflammatory, and OATP1B1, Pec, J. M. baicalin! Fromm MF R. and khazanov, V. a Bitto a, et al 2004! M. K. Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives Q., and Zhou, X. X J Biol 9-1-2000... ( 5 ):411-419 gasiorowski, K. X or other healthcare professional before using C. 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Knight ’ s instruction it was having that impact, but now I 'm pretty as... Flavocoxid ( Limbrel ), a dual inhibitor of cyclooxygenase and 5-lipoxygenase, blunts phenotype... ; 12 ( 5 ):727-733 water pill or `` diuretic. 49 ( 3 ):507-513 ):507-513 traditionally! Skullcap along with medications used for treating eczema, asthma, Arthritis and allergy baicalein...