View abstract. View abstract. View abstract. Int J Epidemiol. Cochrane.Database.Syst.Rev 2000;(2):CD000183. View abstract. The Italian Longitudinal Study on Aging. View abstract. But Taking folic acid with blood pressure medication does not seem to lower blood pressure more than taking only blood pressure medicine. View abstract. Kendall, A. C., Jones, E. E., Wilson, C. I., Shinton, N. K., and Elwood, P. C. Folic acid in low birthweight infants. Drake S, Lampasona V, Nicks HL, Schwarzmann SW. Pentamidine isethionate in the treatment of Pneumocystis carinii pneumonia. 2012;8(1):13-19. Dev Med Child Neurol 1986;28:624-7. Gandy, G. and Jacobson, W. Influence of folic acid on birthweight and growth of the erythroblastotic infant. Rev Neurol. This supplement is very affordable. Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12. The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence. Liem, A. H., van Boven, A. J., Veeger, N. J., Withagen, A. J., Robles de Medina, R. M., Tijssen, J. G., and van Veldhuisen, D. J. Efficacy of folic acid when added to statin therapy in patients with hypercholesterolemia following acute myocardial infarction: a randomised pilot trial. Halsted CH, Gandhi G, Tamura T. Sulfasalazine inhibits the absorption of folates in ulcerative colitis. Effect of homocysteine interventions on the risk of cardiocerebrovascular events: a meta-analysis of randomised controlled trials. Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lopez-Jaramillo, P., Delgado, F., Jacome, P., Teran, E., Ruano, C., and Rivera, J. Calcium supplementation and the risk of preeclampsia in Ecuadorian pregnant teenagers. 2020: 23(16):2973-2982. View abstract. Zhu, S., Mason, J., Shi, Y., Hu, Y., Li, R., Wahg, M., Zhou, Y., Jin, G., Xie, Y., Wu, G., Xia, D., Qian, Z., Sohg, H., Zhang, L., Russell, R., and Xiao, S. The effect of folic acid on the development of stomach and other gastrointestinal cancers. Women who have had a previous neural tube defect-affected pregnancy should take 400 micrograms of folic acid per day when not planning a pregnancy, and 4000 micrograms per day starting one month before they start trying to become pregnant. Clarke, R., Lewington, S., Sherliker, P., and Armitage, J. Wrone, E. M., Hornberger, J. M., Zehnder, J. L., McCann, L. M., Coplon, N. S., and Fortmann, S. P. Randomized trial of folic acid for prevention of cardiovascular events in end-stage renal disease. Feigelson, H. S., Jonas, C. R., Robertson, A. S., McCullough, M. L., Thun, M. J., and Calle, E. E. Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort. 2007;3:Doc11. Naderer O, Nafziger AN, Bertino JS. Lewis, S. J., Lawlor, D. A., Davey, Smith G., Araya, R., Timpson, N., Day, I. N., and Ebrahim, S. The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis. 2009;9 Suppl 1:S3. View abstract. Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients. View abstract. Deijen, J. View abstract. Am J Clin Nutr 1988;47(3):413-419. Hemodial.Int 2007;11(2):210-216. View abstract. Smith AD. Source Naturals MegaFolinic contains folinic acid rather than folic acid. 2006;154(6):1169-1174. Clarke, R., Lewington, S., and Landray, M. Homocysteine, renal function, and risk of cardiovascular disease. N.Engl.J Med 9-19-1985;313(12):709-715. View abstract. Wald, D. S., Kasturiratne, A., and Simmonds, M. Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials. Deol, P. S., Barnes, T. A., Dampier, K., John, Pasi K., Oppenheimer, C., and Pavord, S. R. The effects of folic acid supplements on coagulation status in pregnancy. A., Tang, M. X., Shea, S., Miller, J., Green, R., and Mayeux, R. Plasma homocysteine levels and risk of Alzheimer disease. View abstract. 1990;10(3):149-152. Bulloch RE, Lovell AL, Jordan VMB, McCowan LME, Thompson JMD, Wall CR. Helicobacter. Roswall N, Olsen A, Christensen J, et al. Serum folate and chronic fatigue syndrome. JAMA 1995;274:1049-57. Ueland PM, Refsum H, Beresford SA, Vollset SE. View abstract. View abstract. J Obstet Gynaecol Can. View abstract. Chou, Y. C., Wu, M. H., Yu, J. C., Lee, M. S., Yang, T., Shih, H. L., Wu, T. Y., and Sun, C. A. Its quality and affordability make it one of the better folic acid supplements available today. Stamp LK, O'Donnell JL, Frampton C, et al. Prenatal multivitamins also contain folic acid. View abstract. View abstract. View abstract. 2-16-2010;50(4):235-244. High amounts of homocysteine in the blood caused by the drug fenofibrate. Can.Med Assoc J 8-15-1984;131(4):273-4, 276. View abstract. Am J Clin Nutr 2000;71:1448-54. The quality, affordability, and practicality of Nature’s Blend Folic acid set it apart from competitors. View abstract. 2013 4;10(2):590-605. View abstract. 2010;14(32):1-206. Bertagnolli, M. M., Eagle, C. J., Zauber, A. G., Redston, M., Solomon, S. D., Kim, K., Tang, J., Rosenstein, R. B., Wittes, J., Corle, D., Hess, T. M., Woloj, G. M., Boisserie, F., Anderson, W. F., Viner, J. L., Bagheri, D., Burn, J., Chung, D. C., Dewar, T., Foley, T. R., Hoffman, N., Macrae, F., Pruitt, R. E., Saltzman, J. R., Salzberg, B., Sylwestrowicz, T., Gordon, G. B., and Hawk, E. T. Celecoxib for the prevention of sporadic colorectal adenomas. Washington, DC: National Academy Press, 2000. View abstract. Kennedy, D. A., Stern, S. J., Moretti, M., Matok, I., Sarkar, M., Nickel, C., and Koren, G. Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. J Am Diet Assoc 1999;99:285. 1989;149(1):65-67. Nutr Cancer 2009;61(4):447-456. View abstract. View abstract. Int.J.Cardiol. Folic acid can be taken through supplements or foods. 6-1-1975;122(3):332-336. van Dijk SC, Enneman AW, Swart KM, et al. 2017;354(4):379-387. View abstract. View abstract. Eur J Cancer Prev 1997;6:S43-5. Depression and tetrahydrobiopterin: the folate connection. Folic acid is the form of folate that manufacturers add to vitamin supplements and fortified foods. Biochem J 1992;282:197-202. Indian Heart J 2000;52(7 Suppl):S59-S64. 1994;14(3):465-470. View abstract. Coppen, A., Chaudhry, S., and Swade, C. Folic acid enhances lithium prophylaxis. Wolff, T., Witkop, C. T., Miller, T., and Syed, S. B. Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force. J Pediatr 2004;144(4):500-504. Ericson, U., Borgquist, S., Ivarsson, M. I., Sonestedt, E., Gullberg, B., Carlson, J., Olsson, H., Jirstrom, K., and Wirfalt, E. Plasma folate concentrations are positively associated with risk of estrogen receptor beta negative breast cancer in a Swedish nested case control study. Folic acid is one of the B vitamins found in foods such as leafy green vegetables, fruits, dried beans, and peas. Williams, C., Kingwell, B. B., Robien, K., Rohan, T. E., Schatzkin, A., Stevens, V. L., Stolzenberg-Solomon, R. Z., Virtamo, J., Wolk, A., Ziegler, R. G., and Smith-Warner, S. A. Folate intake and risk of pancreatic cancer: pooled analysis of prospective cohort studies. Lancet Neurol. View abstract. Gut 1975;16:93-8. Thompson, S. J., Torres, M. E., Stevenson, R. E., Dean, J. H., and Best, R. G. Periconceptional multivitamin folic acid use, dietary folate, total folate and risk of neural tube defects in South Carolina. J.Am.Coll.Nutr. View abstract. BMC Med. 2010;27(3):915-918. View abstract. Carcinogenesis 2008;29(2):356-362. 2012;11:75. A. and Bhutta, Z. Folate for oral contraceptive users may reduce cervical cancer risk. Taliani U, Camellini A, Bernardi P, et al. 2000;26(3):291-295. View abstract. Fruzzetti, F. Beyaz(R): an oral contraceptive fortified with folate. View abstract. View abstract. Effects of oral isotretinoin on serum folic acid levels. Effect of folic acid supplementation on biochemical indices in overweight and obese men with type 2 diabetes. Schroder H, Clausen N, Ostergard E, Pressler T. Folic acid supplements in vitamin tablets: a determinant of hematological drug tolerance in maintenance therapy of childhood acute lymphoblastic leukemia. There is some evidence that increasing folic acid and folate intake from dietary and supplement sources, along with thiamine, riboflavin, and vitamin B12, might help to prevent cancer of the cervix. J Am Coll Cardiol 1996;27:517-27. Circulation 3-30-2010;121(12):1432-1438. 2012;30(4):227-233. Hankey, G. J. and Eikelboom, J. W. Homocysteine and vascular disease. View abstract. Valera-Gran D, García de la Hera M, Navarrete-Muñoz EM, Fernandez-Somoano A, Tardón A, Julvez J, Forns J, Lertxundi N, Ibarluzea JM, Murcia M, Rebagliato M, Vioque J; Infancia y Medio Ambiente (INMA) Project. Cochrane.Database.Syst.Rev 2001;(3):CD001056. Eur.J Clin.Nutr 1998;52(6):407-411. Malouf, M., Grimley, E. J., and Areosa, S. A. Folic acid with or without vitamin B12 for cognition and dementia. Am J Clin Nutr 2007;85:1586-91. Stockley, L. and Lund, V. Use of folic acid supplements, particularly by low-income and young women: a series of systematic reviews to inform public health policy in the UK. Harrison, K. A. Gastroenterology 1986;91:1476-82. 2008;4(12):672-681. Holmes, M. V., Newcombe, P., Hubacek, J. J Am Soc Nephrol 2000;11:1106-16.. View abstract. 2005;19(2):112-124. View abstract. Toole JF, Malinow MR, Chambless LE, et al. Schaefer, E. J., Bongard, V., Beiser, A. S., Lamon-Fava, S., Robins, S. J., Au, R., Tucker, K. L., Kyle, D. J., Wilson, P. W., and Wolf, P. A. Although present in these foods, it can be hard to get enough folic acid from diet alone. 2016;23(1):32-9. Brown WT, Cohen IL, Fisch GS, et al. Am J Psychiatry 2002;159:2099-101.. View abstract. Arch Neurol. J Natl Cancer Inst 1985;74:263. View abstract. JAMA 2003;290:476-85.. View abstract. Mooij PN, Thomas CM, Doesburg WH, Eskes TK. View abstract. Although Nature’s Way’s product is more expensive than some competitors, these are some of the better folic acid pills on the market. Disorders of homocysteine metabolism: from rare genetic defects to common risk factors. J Rheumatol 1998;25:36-43. J.Clin Neurosci. Morgan SL, Baggott JE, Vaughn WH, et al. View abstract. Obstet.Gynecol. Folate deficiency associated with drug therapy for tuberculosis. View abstract. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. Shaw, G. M., Schaffer, D., Velie, E. M., Morland, K., and Harris, J. De-Regil, L. M., Fernandez-Gaxiola, A. C., Dowswell, T., and Pena-Rosas, J. P. Effects and safety of periconceptional folate supplementation for preventing birth defects. View abstract. Wang, X., Qin, X., Demirtas, H., Li, J., Mao, G., Huo, Y., Sun, N., Liu, L., and Xu, X. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lappe JM, Travers-Gustafson D, Davies KM, et al. Int J Cardiol 6-12-2007;118(3):345-349. Stolzenberg-Solomon, R. Z., Chang, S. C., Leitzmann, M. F., Johnson, K. A., Johnson, C., Buys, S. S., Hoover, R. N., and Ziegler, R. G. Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Am J Clin Nutr 1982;35:73-82. Best Folic Acid Tablets in India. J Psychopharmacol 2004;18(2):251-256. Righetti, M., Serbelloni, P., Milani, S., and Ferrario, G. Homocysteine-lowering vitamin B treatment decreases cardiovascular events in hemodialysis patients. Stolzenberg-Solomon RZ, Pietinen P, Barrett MJ, et al. (check all that apply), What factors are most important to you? Christen WG, Glynn RJ, Chew EY, et al. Christen WG, Glynn RJ, Chew EY, et al. View abstract. View abstract. Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone. Note: Folic Acid is also commonly known as Vitamin B9. View abstract. View abstract. 2013;6(7):744-52. Wei Sheng Yan.Jiu. Thomas, M. G., Thomson, J. P., and Williamson, R. C. Oral calcium inhibits rectal epithelial proliferation in familial adenomatous polyposis. Am J Med Sci. Schwammenthal, Y. and Tanne, D. Homocysteine, B-vitamin supplementation, and stroke prevention: from observational to interventional trials. B., Ueland, P. M., Nesthus, I., Nygard, O., Schneede, J., Vollset, S. E., and Refsum, H. Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. Taking folic acid might help slow kidney function decline in people with CKD. Arch.Intern.Med. Pediatrics 1980;65(4):683-697. View abstract. View abstract. Melse-Boonstra, A., Verhoef, P., West, C. E., van Rhijn, J. View abstract. Digestion 1998;59(2):148-156. Burland, W. L., Simpson, K., and Lord, J. Am J Clin Nutr 2007;85(2):465-473. 2003;16(3):156-159. Stroke 2009;40(3):730-736. 2017;96(42):e8182. Graham I. Interactions between homocysteinaemia and conventional risk factors in vascular disease. Help our supplement user ranking system by leaving your vote below. View abstract. Berg MJ, Fincham RW, Ebert BE, et al. View abstract. Folic Acid Tablets, USP, 1 mg, are supplied as round, yellow tablets imprinted “AN” and “361” on one side and scored on the other side. Available at: https://wayback.archive-it.org/7993/20171114183729/https://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm072855.htm. View abstract. View abstract. View abstract. Moodley J and Norman RJ. Birth Defects Res A Clin Mol.Teratol. A., and Uauy, Dagach R. [Effect of folate and related nutrients on cognitive function in older people; systematic review]. Alter HJ, Zvaifler NJ, Rath CE. Relationship between plasma homocysteine and vitamin status in the Framingham study population. 2011;30(3):297-302. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Shojania AM. Toxicity caused by the drug methotrexate. Curr Atheroscler Rep 2001;3:54-63. Cochrane.Database.Syst.Rev 2008;(4):CD004514. Am.J Med.Genet.A 4-1-2008;146(7):803-812. View abstract. J Cardiovasc.Risk 1998;5(4):249-255. Am J Clin Nutr 2004;79(3):424-429. Antimicrob Agents Chemother 1997;41:2466-70. View abstract. Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. J.Am.Coll.Nutr. Ann Trop Med Parasitol. View abstract. Nutrition and vascular dementia. 1994;84(3):349-353. Case study: folate bioavailability. Thus, many believe that increasing natural folate intake from foods should be the focus, although there are still some reasons to take folic acid supplements. The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis. View abstract. NORVIT: Homocysteine lowering and cardiovascular events after acute myocardial infarction. Circulation 2001;104:1086-8. Sommer, B. R., Hoff, A. L., and Costa, M. Folic acid supplementation in dementia: a preliminary report. Ann.Intern.Med 9-7-1999;131(5):363-375. Eur.J.Pediatr. BY MOUTH: Did you or will you purchase this product in-store or online? 2013;32(5):722-7. Settlement Reached for Health Claim Relating B Vitamins and Vascular Disease. 1993;13(9):1253-1260. van der Dijs FP, Fokkema MR, Dijck-Brouwer DA, et al. Am J Dig Dis 1972;17:731-4. Am J Clin Nutr 2005;82(3):636-643. Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Porcellini, E., and Licastro, F. Homocysteine and folate as risk factors for dementia and Alzheimer disease. Folic acid-an innocuous means to reduce plasma homocysteine. Smithells, R. W. Can vitamins prevent neural tube defects? View abstract. Efficacy of folic acid therapy on the progression of chronic kidney disease: The renal substudy of the China stroke primary prevention trial. Impact of folic acid fortification. A., Breedveld, F. C., and van de Putte, L. B. Eur.J.Cancer Prev. Baron JA, Sandler RS, Haile RW, et al. Folate is a B-vitamin naturally found in some foods. View abstract. Klipstein FA, Berlinger FG, Reed LJ. Rev Recent Clin Trials 2008;3(2):79-88. Trial of calcium to prevent preeclampsia. A. Homocysteine, vitamins, and vascular disease prevention: more negative results. Folic acid is vital to the normal growth of your baby's spine, brain and skull. Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention. Glaxo-Wellcome, Inc. Daraprim package insert. View abstract. This category only includes cookies that ensures basic functionalities and security features of the website. Clin Nephrol 1999;51:108-15. Morgan SL, Baggott JE, Lee JY, Alarcón GS. 1996;87(3-4):141-149. A dual-isotope-labeling method of studying the bioavailability of hexaglutamyl folic acid relative to that of monoglutamyl folic acid in humans by using multiple orally administered low doses. Clin J Sport Med 2010;20(3):205-210. Am.J Clin.Nutr 2006;84(4):880-887. 2012;27(1):90-102. Snowdon DA, Tully CL, Smith CD, et al. Phenobarbital (Luminal) is used for seizures. Qin, X., Huo, Y., Langman, C. B., Hou, F., Chen, Y., Matossian, D., Xu, X., and Wang, X. Folic acid therapy and cardiovascular disease in ESRD or advanced chronic kidney disease: a meta-analysis. Dockerty, J. D., Herbison, P., Skegg, D. C., and Elwood, M. Vitamin and mineral supplements in pregnancy and the risk of childhood acute lymphoblastic leukaemia: a case-control study. Homocysteine, B vitamins, and cognitive deficit in the elderly. Am J Med Genet 1983;35(243):82A. 1990;163(4 Pt 1):1124-1131. 2009;54(3):478-489. View abstract. Albert, C. M., Cook, N. R., Gaziano, J. M., Zaharris, E., MacFadyen, J., Danielson, E., Buring, J. E., and Manson, J. E. Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial. View abstract. J Am Soc Nephrol 2000;11:1106-16. Obeid, R., Kasoha, M., Kirsch, S. H., Munz, W., and Herrmann, W. Concentrations of unmetabolized folic acid and primary folate forms in pregnant women at delivery and in umbilical cord blood. 2010;16(3):161-166. Presented at a meeting of the American Heart Association, late breaking trials; New Orleans. Taking folic acid by mouth seems to improve symptoms of vitiligo. Rev.Chil.Pediatr. Obeid R, FinkGeisel U, Eckert R, and Herrmann W. Effect of the Bvitamins on cognitive function in elderly people with mild cognitive dysfunction. Proper timing can make all the difference in the world. 2010;39 Suppl 1:i110-i121. Cancer Res 2-15-2005;65(4):1606-1614. Nutr.Clin Pract. Int J Cardiol 2004;93(2-3):175-179. Taking folic acid does not appear to improve the antidepressant effects of lithium in people with bipolar disorder. Ma J, Stampfer MJ, Giovannucci E, et al. Blood Purif. Am J Clin Nutr 2002;75:785-6. 1982;9(3):275-280. Atherosclerosis 1990;81(1):51-60. View abstract. Clin Neuropharmacol 1995;18:165-82. View abstract. 12-3-1999;87(4):366-368. Ray, J. G., O'Brien, T. E., and Chan, W. S. Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis. View abstract. The nutrition of expectant and nursing mothers in relation to maternal and infant mortality and morbidity. J Matern Fetal Neonatal Med. Am.J.Obstet.Gynecol. Heinz, J., Kropf, S., Luley, C., and Dierkes, J. Homocysteine as a risk factor for cardiovascular disease in patients treated by dialysis: a meta-analysis. It’s a man-made version of folate, a naturally occurring B vitamin found in many foods. Folic acid may interfere with the toxic and therapeutic effects of methotrexate. Folic acid is known as a B vitamin that aids the body in making healthy new cells. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Atherosclerosis 2005;181(1):131-135. Cancer Epidemiol.Biomarkers Prev. View abstract. 2012;28(2):221-229. Lin RJ, Krall R, Westerberg BD, et al. Am J Alzheimers.Dis.Other Demen. Chin Med J 2003;116:15-19. Bedford Laboratories. Am J Clin Nutr 2001;73:1027-33.. View abstract. FREE Delivery on your first order shipped by Amazon. Reduction of incidence of prematurity by folic acid supplementation in pregnancy. Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study. World J Gastroenterol 7-28-2008;14(28):4492-4498. View abstract. Am.J.Med.Genet.A 6-1-2005;135(2):120-125. View abstract. Br Med J (Clin Res Ed) 1-30-1988;296(6618):313-316. The effects of folate supplementation on some coagulation parameter and oxidative status surrogates. Suitor CW, Bailey LB. Blood 1971;38:405-16. Gillberg C, Wahlstrom J, Johansson R, et al. Expert Opin Investig Drugs 2000;9:2637-51. 5. 2007;(4):CD000978. Information from this source is evidence-based and objective, and without commercial influence. Rush, D., Stein, Z., and Susser, M. A randomized controlled trial of prenatal nutritional supplementation in New York City. Ratanachu-Ek, S. Effects of multivitamin and folic acid supplementation in malnourished children. Bengt E. Gustafsson memorial lecture. Eur J Clin Invest 2003;33(11):933-940. J Nutr 2002;132(8 Suppl):2367S-2372S. Am J Kidney Dis. Luhmann, D., Schramm, S., and Raspe, H. The role of Homocysteine as a predictor for coronary heart disease. Hill MJ. View abstract. With several facilities across the USA and Canada, they have a solid manufacturing and distribution chain. JAMA 10-15-2008;300(15):1774-1783. View abstract. Dierkes J, Domrose U, Bosselmann P, et al. Suzuki, T., Matsuo, K., Hirose, K., Hiraki, A., Kawase, T., Watanabe, M., Yamashita, T., Iwata, H., and Tajima, K. One-carbon metabolism-related gene polymorphisms and risk of breast cancer. Neurology 6-8-2004;62(11):1972-1976. Mackey, A. D. and Picciano, M. F. Maternal folate status during extended lactation and the effect of supplemental folic acid. Hagerman, R. J., Murphy, M. A., and Wittenberger, M. D. A controlled trial of stimulant medication in children with the fragile X syndrome. Galeone C, Edefonti V, Parpinel M, Leoncini E, Matsuo K, Talamini R, Olshan AF, Zevallos JP, Winn DM, Jayaprakash V, Moysich K, Zhang ZF, Morgenstern H, Levi F, Bosetti C, Kelsey K, McClean M, Schantz S, Yu GP, Boffetta P, Lee YC, Hashibe M, La Vecchia C, Boccia S. Folate intake and the risk of oral cavity and pharyngeal cancer: a pooled analysis within the International Head and Neck Cancer Epidemiology Consortium. Modern Nutrition in Health and Disease. View abstract. Gynecol.Obstet.Invest 1981;12(6):294-304. Association between B-group vitamins and venous thrombosis: systematic review and meta-analysis of epidemiological studies. Am J Clin Nutr 2002;75:275-82.. View abstract. View abstract. One tablet daily of this effective product is enough to get the many folic acid benefits that we mentioned before. Riddell LJ, Chisholm A, Williams S, Mann JI. Baltimore, MD: Williams & Wilkins, 1999. View abstract. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. 1976;12(12):1410-1417. Am J Clin Nutr 2004;80(3):700-704. Arch Gynecol.Obstet 1994;255(3):131-139. A skin disorder that causes white patches to develop on the skin (vitiligo). 1993;71(12):993-998. View abstract. 2012;11(12):1428-33. Longstreth GF, Green R. Folate status in patients receiving maintenance doses of sulfasalazine. View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: Chen, G., Song, X., Ji, Y., Zhang, L., Pei, L., Chen, J., Liu, J., Li, C., and Zheng, X. Some experts believe that folic acid is not absorbed as easily as folate, which can potentially lead to unhealthy levels of unmetabolized folic acid in the bloodstream.